| Program | Grantee | Infrastructure Related Project | Total Award | Year of Award | Status at End of FY 2022 |
| Capital Program | Bay Path College | Planning Grant | $50,000 | FY 2013 | Completed |
| Capital Program | Bay Path University | Equipment for Workforce Training | $499,996 | FY 2015 | Completed |
| Capital Program | Baystate Health | Clinical Trials Unit | $3,949,912 | FY 2019 | Completed |
| Capital Program | BayState Medical Center | Health Informatics and Technology Innovation Center (HITIC) | $5,500,000 | FY 2013 | Completed |
| Workforce Capital | Benjamin Franklin Cummings Institute of Technology | Biotechnology Program | $749,936 | FY 2022 | Ongoing |
| Capital Program | Berkshire Community College | Equipment for Workforce Training | $499,998 | FY 2015 | Completed |
| Capital Program | Berkshire Innovation Center | Life Sciences Incubator - Berkshire Innovation Center (BIC) | $11,970,000 | FY 2018 | Completed |
| Bits to Bytes | Beth Israel Deaconess Medical Center | Creating a Large Clinically Annotated Dataset of Antibody and TCR Repertoires in Cancer and Infectious Disease | $750,000 | FY 2021 | Ongoing |
| Capital Program | Beth Israel Deaconess Medical Center | Organ on chip facility in a hospital setting | $1,705,471 | FY 2020 | Ongoing |
| Women's Health | Beth Israel Deaconess Medical Center | The Lactation Lab: Improving the health of two generations by optimizing breastfeeding | $857,563 | FY 2020 | Ongoing |
| Women's Health Innovation | Beth Israel Deaconess Medical Center | Develop first in class agents that mitigate the underlying causes of preeclampsia | $110,000 | FY 2021 | Ongoing |
| Capital Program | Beth Israel Deaconess Medical Center | Innovative Glycoscience for Diagnostic and Therapeutic Advances | $1,401,046 | FY 2022 | Ongoing |
| Bits to Bytes | Beth Israel Deaconess Medical Center | Advance the development of diagnostic and prognostic biomarkers for NASH | $750,000 | FY 2022 | Ongoing |
| Novel Therapeutics Delivery | Beth Israel Deaconess Medical Center | Hepatocyte-specific delivery of RNA therapy for liver failure | $750,000 | FY 2022 | Ongoing |
| Novel Therapeutics Delivery | Beth Israel Deaconess Medical Center | SARS-CoV-2 Variants, Viral Pneumonia, Encephalitis, Sentinel Discovery, Diagnostics and Technology Evaluation | $749,687 | FY 2022 | Ongoing |
| Bits to Bytes | Beth Israel Deaconess Medical Center | Echocardiogram and electrocardiogram extension to the MIMIC database | $636,938 | FY 2020 | Completed |
| Capital Program | Beth Israel Deaconess Medical Center | Spatial Technologies Unit in the Precision Medicine Initiative at BIDMC | $3,307,757 | FY 2021 | Ongoing |
| Capital Program | BioBuilder | Learning Lab at LabCentral | $500,000 | FY 2017 | Ongoing |
| Bits to Bytes | Boston Children’s Hospital | Precision Nutrition for Term-born Infants | $749,950 | FY 2021 | Ongoing |
| Bits to Bytes | Boston Children's Hospital | Subcellular Dynamics | $658,167 | FY 2019 | Completed |
| Capital Program | Boston Children's Hospital | Cell Therapy Center Improvements | $4,014,031 | FY 2013 | Completed |
| Capital Program | Boston Children's Hospital | Center for Accelerated Therapeutic Development | $1,523,992 | FY 2019 | Completed |
| Capital Program | Boston Children's Hospital | Human Neuron Core Improvements | $2,263,133 | FY 2015 | Completed |
| Women's Health Innovation | Boston Medical Center | Non-hormonal female contraceptive | $200,000 | FY 2021 | Ongoing |
| Capital Program | Boston University | Biomedical Lab and Clinical Sciences Program | $180,000 | FY 2015 | Completed |
| Novel Therapeutics Delivery | Boston University | Glycosylation analysis techniques and software to enable generation of more effective Influenza A virus vaccines | $749,349 | FY 2020 | Completed |
| Women's Health Innovation | Boston University | Development of novel breast cancer therapies by targeting epigenetic dysregulation in tumors | $200,000 | FY 2021 | Ongoing |
| Capital Program | Boston University | Business Innovation Center (BIC) at the BU Photonics Center | $363,750 | FY 2015 | Completed |
| Capital Program | Boston University Medical School | Center for Translational Neurotrauma Imaging | $4,896,000 | FY 2019 | Completed |
| Capital Program | Boston University Medical School | Lung Regeneration Initiative (LRI) Stem Cell Facility | $1,743,648 | FY 2015 | Completed |
| Capital Program | Brigham and Women’s Hospital | High Field Mass Spectometry | $5,000,000 | FY 2019 | Completed |
| Capital Program | Brigham and Women’s Hospital | MAGNUS – next-generation MRI scanner to advance brain research in Massachusetts | $3,026,942 | FY 2022 | Ongoing |
| Capital Program | Brigham and Women’s Hospital | Enabling Computational and Quantitative Microbiology to Promote Commonwealth Innovation | $3,346,155 | FY 2022 | Ongoing |
| Women's Health | Brigham and Women’s Hospital | The Multiomic Multiple Sclerosis Brain | $748,114 | FY 2022 | Ongoing |
| Bits to Bytes | Brigham and Women's Hospital | Artificial Intelligence Guidance for High-Yield Point-of-Care Ultrasound Applications | $749,498 | FY 2021 | Ongoing |
| Bits to Bytes | Brigham and Women's Hospital | Natural History of Neurofilament Concentrations and Mechanisms of Healthy Aging | $728,559 | FY 2020 | Ongoing |
| Capital Program | Brigham and Women's Hospital | Host-Microbiome Center | $2,603,537 | FY 2015 | Completed |
| Women's Health | Brigham and Women's Hospital | The Lactation Lab: Improving the health of two generations by optimizing breastfeeding | $268,743 | FY 2020 | Ongoing |
| Bits to Bytes | Brigham and Women's Hospital | Serum miRNA | $750,000 | FY 2019 | Completed |
| Capital Program | Bristol Community College | Cleanroom-like suite educational space | $4,400,000 | FY 2017 | Completed |
| Workforce Capital | Bristol Community College | Analytical Chemistry Training Laboratory | $543,363 | FY 2022 | Ongoing |
| Bits to Bytes | Broad Institute | Cell Painting | $821,000 | FY 2019 | Completed |
| Bits to Bytes | Broad Institute | Data driven approaches to cardio diseases | $750,000 | FY 2019 | Completed |
| Capital Program | Bunker Hill Community College | Equipment for Workforce Training | $200,000 | FY 2013 | Completed |
| Capital Program | Cape Cod Community College | Equipment for Workforce Training | $394,912 | FY 2014 | Completed |
| Workforce Capital | Cape Cod Community College | AA Biology/Biotechnology Certificate | $221,670 | FY 2022 | Ongoing |
| Capital Program | City of Taunton | Development of Life Sciences Center in City of Taunton | $55,000 | FY 2014 | Completed |
| Capital Program | Dana-Farber Cancer Institute | Molecular Cancer Imaging Facility (MCIF) | $10,000,000 | FY 2012 | Completed |
| Capital Program | Dana-Farber Cancer Institute | Advanced Cell Therapy Unit at the Cell Manipulation Core Facility | $4,629,019 | FY 2017 | Completed |
| Capital Program | Dana-Farber Cancer Institute | Mass Spectrometry Metabolomics Solutions. Charting Metabolic Disease Development and Therapeutic Outcomes | $1,824,016 | FY 2021 | Completed |
| Women's Health | Dana-Farber Cancer Institute | Leveraging Digital Pathology to Identify and Cure High Risk Breast Cancer | $748,075 | FY 2021 | Ongoing |
| Women's Health Innovation | Dana-Farber Cancer Institute | Microdevice to measure drug response in ovarian cancer patients | $200,000 | FY 2021 | Ongoing |
| Women's Health Innovation | Dana-Farber Cancer Institute | Study of microbiome in relation to breast cancer and treatment options | $200,000 | FY 2021 | Ongoing |
| Capital Program | Dana-Farber Cancer Institute | Center for Emergent Drug Targets | $2,811,397 | FY 2022 | Ongoing |
| Capital Program | Dean College | Biology Laboratory Equipment | $297,030 | FY 2017 | Completed |
| Capital Program | Framingham State University | Science Center Laboratories Renovation | $454,000 | FY 2017 | Completed |
| Capital Program | Framingham State University | Hemenway Hall Science Center | $3,000,000 | FY 2014 | Completed |
| Workforce Capital | Framingham State University | Professional Science Master’s (PSM) in Biotechnology, with concentration in Quality Assurance | $20,600 | FY 2022 | Ongoing |
| Capital Program | Framingham Wastewater and Pumping Station | Pleasant Street Water Transmission Line | $12,860,534 | FY 2009 | Completed |
| Capital Program | Gloucester Marine Genomics Institute | Marine Genomics Research Institute at Gloucester Harbor | $2,744,219 | FY 2017 | Completed |
| Capital Program | Gloucester Marine Genomics Institute | Cell Culture Lab | $174,383 | FY 2019 | Completed |
| Workforce Capital | Gloucester Marine Genomics Institute | Biomanufacturing Expansion and Program Scale | $578,824 | FY 2022 | Ongoing |
| Bits to Bytes | Harvard Medical School | Metabolomics and Big Data | $750,000 | FY 2019 | Completed |
| Capital Program | Harvard Medical School | Laboratory of Systems Pharmacology expansion | $4,345,000 | FY 2017 | Completed |
| Women's Health | Harvard Medical School | Pathfinder: Studying Lymphocyte Repertoire Dynamics During Pregnancy in Autoimmune Sufferers | $735,000 | FY 2021 | Ongoing |
| Capital Program | Harvard Medical School | Laboratory Systems of Pharmacology (LSP) | $4,999,921 | FY 2013 | Completed |
| Capital Program | Harvard School of Public Health | BioBank for Microbiome Research (BIOM-Mass) | $4,912,307 | FY 2017 | Completed |
| Bits to Bytes | Harvard School of Public Health | Microbiome in chronic disease management | $688,533 | FY 2019 | Completed |
| Bits to Bytes | Harvard School of Public Health | High Throughput Laboratory for Advanced Immunological Testing for Clinical and Public Health Surveillance | $737,950 | FY 2021 | Ongoing |
| Novel Therapeutics Delivery | Harvard School of Public Health | Advancing CNS Therapeutic Delivery via ARMMs | $268,633 | FY 2020 | Ongoing |
| Capital Program | Holyoke Community College | Center for Life Sciences | $3,800,000 | FY 2013 | Completed |
| Capital Program | Holyoke Community College | Equipment for Workforce Training | $300,000 | FY 2015 | Completed |
| Capital Program | Institute for Protein Innovation | Open-source Antibody Discovery platform | $5,000,000 | FY 2017 | Completed |
| Workforce Capital | Jewish Vocational Service, Inc. (JVS) | Bridges to College and Careers Biotechnology Pathway Expansion: Boston Healthcare and Life Sciences Career Institute | $607,983 | FY 2022 | Ongoing |
| Capital Program | Joslin Diabetes Center | Translational Center for the Cure of Diabetes | $5,000,000 | FY 2012 | Completed |
| Workforce Capital | Just A Start | The Rindge Commons Economic Mobility Hub - Bioscience Lab | $740,970 | FY 2022 | Ongoing |
| Capital Program | Just-A-Start | Equipment | $49,992 | FY 2015 | Completed |
| Capital Program | Just-A-Start | Equipment | $46,079 | FY 2014 | Completed |
| Capital Program | Lab Central 238 | Build-out facility to bridge gaps as startups design and test the processes prior to full-scale GMP production | $5,000,000 | FY 2019 | Completed |
| Capital Program | LabCentral | Accelerator Lab | $4,955,515 | FY 2013 | Completed |
| Capital Program | LabCentral | Accelerator Lab Expansion | $5,000,000 | FY 2014 | Completed |
| Capital Program | Lahey Hospital and Medical Center | Image-guided Therapy Innovation Center | $4,000,000 | FY 2022 | Ongoing |
| Workforce Capital | Lasell University | Life Science Program: Biochemistry and Biology Majors | $703,896 | FY 2022 | Ongoing |
| Capital Program | MA Green High Performance Computing Center | Commonwealth Computational Cloud for Data Driven Biology Facility (C3DDB) | $4,540,000 | FY 2013 | Completed |
| Capital Program | Marine Biological Laboratory in Woods Hole | Center for Regenerative Biology and Medicine | $10,000,000 | FY 2009 | Completed |
| Workforce Capital | Mass College of Liberal Arts | Life Sciences at MCLA | $253,542 | FY 2022 | Ongoing |
| Workforce Capital | Mass Maritime Academy | Instrumentation, Operation and Controls (IOC) Engineering Laboratory | $750,000 | FY 2022 | Ongoing |
| Capital Program | Massachusetts Biomedical Initiatives | Expanding the Central MA Biomedical Infrastructure to Grow the Regional Cluster | $3,494,256 | FY 2019 | Completed |
| Capital Program | Massachusetts Biomedical Initiatives | Expansion of Incubator Space | $500,000 | FY 2020 | Completed |
| Capital Program | Massachusetts Biomedical Initiatives | MBI ScaleUp Center Expansion | $3,000,000 | FY 2022 | Ongoing |
| Bits to Bytes | Massachusetts General Hospital | An integrative platform to understand and exploit cancer metabolism | $750,000 | FY 2020 | Completed |
| Capital Program | Massachusetts General Hospital | Transforming Clinical Research for Brain Health | $4,805,000 | FY 2019 | Completed |
| Novel Therapeutics Delivery | Massachusetts General Hospital | High resolution pharmacokinetics: imaging drug delivery from administration to on-target activity (high-res PK DATA) | $749,998 | FY 2020 | Completed |
| Novel Therapeutics Delivery | Massachusetts General Hospital | Advancing CNS Therapeutic Delivery via ARMMs | $481,367 | FY 2020 | Ongoing |
| Women's Health Innovation | Massachusetts General Hospital | Treatment of autoimmune conditions through CAR-T cells | $200,000 | FY 2021 | Ongoing |
| Women's Health Innovation | Massachusetts General Hospital | Single-cell and multiomic approach to molecular and cellular ecosystem to understand women’s health conditions | $197,993 | FY 2021 | Ongoing |
| Capital Program | Massachusetts General Hospital | Mass General Tumor Cartography Center | $4,000,000 | FY 2022 | Ongoing |
| Novel Therapeutics Delivery | Massachusetts General Hospital | High-throughput translational microPET/CT imaging for radiotracer development and drug delivery | $750,000 | FY 2022 | Ongoing |
| Bits to Bytes | Massachusetts General Hospital | Facilitating drug development for neurodegenerative diseases | $666,500 | FY 2020 | Ongoing |
| Bits to Bytes | Massachusetts Institute of Technology | Echocardiogram and electrocardiogram extension to the MIMIC database | $358,918 | FY 2020 | Ongoing |
| Novel Therapeutics Delivery | Massachusetts Institute of Technology | Regioselective conjugation of peptides to the major histocompatibility complex I (MHC I) | $747,427 | FY 2020 | Completed |
| Building Breakthroughs | Massachusetts Institute of Technology | Model Predictive Control for Improved Product Quality in the Production of Viral Vectors- | $732,674 | FY 2019 | Completed |
| Building Breakthroughs | Massachusetts Institute of Technology | Continuous Countercurrent Tangential Chromatography (CCTC) | $750,000 | FY 2019 | Completed |
| Capital Program | Massachusetts Institute of Technology | Technology Platform for Brain Research | $1,838,000 | FY 2015 | Completed |
| NIIMBL | Massachusetts Institute of Technology | Viral Vaccines | $225,612 | FY 2019 | Completed |
| NIIMBL | Massachusetts Institute of Technology | Small-scale Membrane-less Perfusion Bioreactor System | $267,182 | FY 2019 | Completed |
| NIIMBL | Massachusetts Institute of Technology | Blended Learning Cell Therapy Course | $330,200 | FY 2018 | Completed |
| NIIMBL | Massachusetts Institute of Technology | Modularized PAT Online Training Platform to Accelerate the Workforce Innovation in Biopharmaceuticals Manufacturing | $264,164 | FY 2021 | Completed |
| Women's Health | Massachusetts Institute of Technology | Nerve-immune Interactions as A Target of Endometriosis and Adenomyosis therapies | $665,000 | FY 2021 | Ongoing |
| Women's Health Innovation | Massachusetts Institute of Technology | Increasing access to egg freezing through automation | $195,621 | FY 2021 | Ongoing |
| Capital Program | MassBay Community College | Therapeutics and Genomics Training | $500,000 | FY 2019 | Completed |
| Capital Program | MassBay Community College | Planning Grant | $43,920 | FY 2014 | Completed |
| Workforce Capital | MassBay Community College | Center for Biotherapeutics and Genomics Training | $750,000 | FY 2022 | Ongoing |
| NIIMBL | MassBiologics | Improve Lentiviral Vector Biomanufacturing for Cell and Gene Therapy Applications | $447,566 | FY 2018 | Completed |
| NIIMBL | MassBiologics | Viral Vaccines | $185,540 | FY 2019 | Completed |
| Capital Program | MassBiologics-UMass Medical School | Vector Manufacturing Center (VMC) in Mattapan Facility | $5,000,000 | FY 2014 | Completed |
| Workforce Capital | MCPHS University (Mass College of Pharmacy and Health Sciences) | Pharmaceutical Sciences | $630,600 | FY 2022 | Ongoing |
| Capital Program | Merrimack College | Interdisciplinary Imaging and Analytical Science Equipment | $500,000 | FY 2017 | Completed |
| Capital Program | Middlesex Community College | Biotechnology Training Facility | $3,000,000 | FY 2014 | Completed |
| Capital Program | Middlesex Community College | Planning Grant | $36,664 | FY 2013 | Completed |
| Workforce Capital | Middlesex Community College | Biotechnology Technician (AS), Biology Transfer (AS) | $750,000 | FY 2022 | Ongoing |
| Capital Program | Mount Wachusett Community College | Equipment for Workforce Training | $499,146 | FY 2014 | Completed |
| Capital Program | Mt. Wachusett Community College | Medical laboratory technology classroom | $1,646,725 | FY 2017 | Completed |
| Capital Program | Museum of Science | Hall of Human Life Exhibit | $5,000,000 | FY 2012 | Completed |
| Capital Program | Museum of Science | Race to the Vaccine Exhibition | $1,512,062 | FY 2021 | Completed |
| Capital Program | New Bedford Economic Development Council | Regional Incubation Center for Life Science Initiatives | $75,000 | FY 2014 | Completed |
| Capital Program | North Shore Biotech Consortium | Life Sciences Consortium of the North Shore | $5,000,000 | FY 2014 | Completed |
| Workforce Capital | North Shore Biotech Consortium | Enhancing the Life Sciences Workforce Pipeline in the North of Boston Region | $1,657,837 | FY 2022 | Ongoing |
| Capital Program | North Shore InnoVentures | NSIV Expansion | $1,500,000 | FY 2019 | Completed |
| Capital Program | North Shore InnoVentures | Nurturing Strengths and Building Opportunities in Metro-North's Life Science Community | $3,100,000 | FY 2022 | Ongoing |
| Capital Program | Northeastern University | Biopharma Analysis Training Lab | $4,271,867 | FY 2019 | Completed |
| NIIMBL | Northeastern University | Modularized PAT Online Training Platform to Accelerate the Workforce Innovation in Biopharmaceuticals Manufacturing | $375,000 | FY 2021 | Ongoing |
| Novel Therapeutics Delivery | Northeastern University | CNS Delivery of Nucleic Acid Therapeutics using MIND | $749,858 | FY 2021 | Ongoing |
| Bits to Bytes | Northeastern University | Understanding macrophage polarization by data-driven single-cell proteomics | $780,000 | FY 2022 | Ongoing |
| Bits to Bytes | Northeastern University | In Silico design of an arrary chromophores | $750,000 | FY 2019 | Ongoing |
| Capital Program | Northern Essex Community College | Haverhill and Lawrence Labs | $1,242,000 | FY 2013 | Completed |
| Capital Program | Pittsfield Economic Development Authority | Planning Grant | $55,000 | FY 2013 | Completed |
| Capital Program | Quincy College | Workforce Training in Biomanufacturing: Upstream & Downstream Processing | $725,739 | FY 2019 | Completed |
| NIIMBL | Quincy College | Equipment and supplies needed to support new gene and cell therapy training. | $49,928 | FY 2020 | Completed |
| Capital Program | Quincy College | Equipment for Workforce Training | $78,799 | FY 2013 | Completed |
| Capital Program | Quincy College | Equipment for Workforce Training | $499,872 | FY 2014 | Completed |
| Workforce Capital | Quincy College | Biomanufacturing Industry-Aligned Certificate and Degree | $750,000 | FY 2022 | Ongoing |
| Capital Program | Quinsigamond Community College | Capital and Equipment | $4,999,998 | FY 2015 | Completed |
| Capital Program | Quinsigamond Community College | Equipment for Workforce Training | $310,000 | FY 2013 | Completed |
| Capital Program | Quinsigamond Community College | Equipment for Workforce Training | $499,880 | FY 2014 | Completed |
| Capital Program | Regis College | Planning Grant | $50,000 | FY 2013 | Completed |
| Capital Program | Regis College | Equipment for Workforce Training | $355,000 | FY 2015 | Completed |
| Capital Program | Roxbury Community College | Capital and Equipment | $3,000,000 | FY 2015 | Completed |
| Capital Program | Smith College | Equipment - Center for Molecular Biology, Microscopy & Imaging | $489,435 | FY 2017 | Completed |
| Capital Program | Springfield Technical Community College | Biomedical Engineering Lab | $972,850 | FY 2015 | Completed |
| Capital Program | Springfield Technical Community College | Planning Grant | $85,673 | FY 2013 | Completed |
| Capital Program | The Forsyth Institute | Forsyth Center for Salivary Diagnostics (FCSD) | $4,133,215 | FY 2013 | Completed |
| Capital Program | The Forsyth Institute | Host Microbiome Center | $2,210,229 | FY 2015 | Completed |
| Capital Program | The Mansfield Bio-Incubator | Bio-incubator Laboratory infrastructure expansion project | $2,000,000 | FY 2020 | Completed |
| Bits to Bytes | Tufts University | Noninvasive detection of bladder cancer through advanced nanoscale imaging and machine learning analysis | $750,000 | FY 2021 | Ongoing |
| Capital Program | Tufts University | Establishing a state of the art comparative infectious disease pathology core to accelerate translational research | $2,027,244 | FY 2021 | Completed |
| Novel Therapeutics Delivery | Tufts University | Transdermal delivery of monoclonal antibody therapy using macro-porous structured hard microneedle technology | $745,403 | FY 2021 | Ongoing |
| Women's Health | Tufts University | Elucidating sex differences in network aberrations in depression while building equitable infrastructure for research | $251,548 | FY 2021 | Ongoing |
| Capital Program | Tufts/Cummings School of Veterinary Medicine | School of Veterinary Medicine (NE-RBL) | $9,500,000 | FY 2009 | Completed |
| Capital Program | UMass Amherst | Acquisition of Synapt G2-32k Mass Spectrometer for biopharmaceutical | $299,329 | FY 2020 | Completed |
| Capital Program | UMass Amherst | Enhancement of the UMass Amherst Light Microscopy Facility for cutting edge | $515,617 | FY 2020 | Completed |
| Capital Program | UMass Amherst | SampleJet, high throughput sample changing roboto for NMR | $129,900 | FY 2020 | Completed |
| Capital Program | UMass Amherst | MLSC Open Capital Flow Cytometry at UMass Amherst | $1,100,259 | FY 2020 | Completed |
| Women's Health | UMass Amherst | Artificial Intelligence for Menopause Symptoms (AIMS) | $747,225 | FY 2020 | Ongoing |
| Capital Program | UMass Amherst | Life Sciences Laboratory Research Center Complex | $95,000,000 | FY 2013 | Completed |
| Women's Health Innovation | UMass Amherst | Thermal therapeutic to regulate sleeping in menopausal women | $199,911 | FY 2021 | Ongoing |
| Bits to Bytes | UMass Boston | The Oregon-Massachusetts Mammography Database (OMAMA-DB) | $749,834 | FY 2020 | Ongoing |
| Capital Program | UMass Boston | Center for Personalized Cancer Therapy (CPCT) | $9,878,503 | FY2011/ FY2014 | Completed |
| Capital Program | UMass Boston | Conversion of Venture Development Center (VDC) | $588,848 | FY 2014 | Completed |
| Capital Program | UMass Boston | NextGen Sequencing at the Next Level: UMass Boston CPCT Genomic Core | $387,808 | FY 2020 | Completed |
| Capital Program | UMass Boston | Biophysical Instrumentation Core for Molecular Interactions, Thermodynamics, and Structure for Life Sciences | $1,647,201 | FY 2022 | Ongoing |
| Bits to Bytes | UMass Boston | Development of a bispecific antibody for treatment of tumors that targets EGFR, NRP1 and resistant to heparin binding | $749,993 | FY 2022 | Ongoing |
| Bits to Bytes | UMass Chan Medical School | AI in high resolution neurovascular imaging | $750,000 | FY 2019 | Completed |
| Bits to Bytes | UMass Chan Medical School | Spatial transcriptomic approaches to map neuroinflammation in neurodegenerative disease | $750,000 | FY 2020 | Ongoing |
| Capital Program | UMass Chan Medical School | Albert Sherman Center | $90,000,000 | FY 2010 | Completed |
| Capital Program | UMass Chan Medical School | Titan Krios Microscope for the MACryoEM | $5,000,000 | FY 2015 | Completed |
| Capital Program | UMass Chan Medical School | UMass Chan Medical School Positron Emission Tomography Center | $1,370,315 | FY 2020 | Completed |
| Capital Program | UMass Chan Medical School | Enhancing Innovation in Drug Discovery at UMass Chan Medical School | $926,305 | FY 2020 | Completed |
| Capital Program | UMass Chan Medical School | Massachusetts Center for High-Resolution Electron Cryomicroscopy | $2,797,610 | FY 2021 | Completed |
| Women's Health | UMass Chan Medical School | Improving Breast Cancer Diagnosis Using Artificial Intelligence in Mammography Screenings | $750,000 | FY 2020 | Ongoing |
| Women's Health | UMass Chan Medical School | Breast Cancer Detection Empowered by Contrast Agents, Spectral CT, and Machine Learning | $159,000 | FY 2020 | Ongoing |
| Capital Program | UMass Chan Medical School | Enabling nanoscale imaging of viruses of pandemic potential at UMCMS | $2,017,168 | FY 2022 | Ongoing |
| Capital Program | UMass Dartmouth | Massachusetts Accelerator for Biomanufacturing (MAB) | $20,600,000 | FY 2012 | Completed |
| Capital Program | UMass Dartmouth | Advanced Technology Manufacturing Center (ATMC) | $11,400,000 | FY 2012 | Completed |
| Workforce Capital | UMass Dartmouth | Stepping Stones: Achieving Greater Diversity in Life Sciences through Laboratory Science | $749,966 | FY 2022 | Ongoing |
| Building Breakthroughs | UMass Lowell | Integrated Continuous Biopharma Manufacturing | $637,601 | FY 2019 | Completed |
| Capital Program | UMass Lowell | Perry Hall build out for BME Program Laboratories | $5,000,000 | FY 2017 | Completed |
| NIIMBL | UMass Lowell | Lyophilization Scale-up | $1,000,000 | FY 2018 | Completed |
| NIIMBL | UMass Lowell | Lyophilization Scale-up (Additional funding) | $299,779 | FY 2019 | Completed |
| NIIMBL | UMass Lowell | Bioreactor Trace Meal Quantification | $246,754 | FY 2018 | Completed |
| NIIMBL | UMass Lowell | Developing a Fluorescence-based Multi-step IEX-HPLC Method for Quantification of Capsid in AAV products | $216,090 | FY 2021 | Completed |
| Capital Program | UMass Lowell | Emerging Technologies and Innovation Center (ETIC) | $10,000,000 | FY 2012 | Completed |
| Capital Program | UMass Lowell | Big Company/Little Company (M2D2 Innovation Hub) | $5,046,592 | FY 2014 | Completed |
| Capital Program | UMass Lowell | Establishing a public small animal imaging core research facility for Northeast Massachusetts | $1,132,949 | FY 2020 | Completed |
| Women's Health | UMass Lowell | Breast Cancer Detection Empowered by Contrast Agents, Spectral CT, and Machine Learning | $591,000 | FY 2020 | Ongoing |
| Workforce Capital | UMass Lowell | Biomanufacturing Workforce Development Program | $729,414 | FY 2022 | Ongoing |
| Capital Program | Venture Cafe | Capital Improvements to District Hall | $347,000 | FY 2014 | Completed |
| Capital Program | Wellesley College | Planning Grant - Renovation of Life Sciences Center | $49,376 | FY 2015 | Completed |
| Capital Program | Western New England University | Equipment for Workforce Training | $497,449 | FY 2014 | Completed |
| Capital Program | Westfield State University | Planning Grant - Center for Biotechnology at WSU | $43,564 | FY 2017 | Completed |
| Women's Health | Westfield State University | Predictive modeling to create "bioprofiles": for use in personalized medicine in women's health | $750,000 | FY 2020 | Ongoing |
| Bits to Bytes | Whitehead Institute for Biomedical Research | Integrating CRISPR-based screens with genetic risk data to elucidate CNS cell dysfunction in multiple sclerosis | $250,090 | FY 2022 | Ongoing |
| Building Breakthroughs | Worcester Polytechnic Institute | Recombinant Adeno-Associated Virus | $566,815 | FY 2019 | Completed |
| Capital Program | Worcester Polytechnic Institute | Cell Engineering Research Accelerator @ WPI | $877,314 | FY 2020 | Completed |
| Women's Health Innovation | Worcester Polytechnic Institute | Increase understanding of maternal-fetal interface through lipid-based models | $137,542 | FY 2021 | Ongoing |
| Workforce Capital | Worcester Polytechnic Institute | Strengthening and Expanding BETC Workforce Engagement | $750,000 | FY 2022 | Ongoing |
| Capital Program | Worcester Polytechnic Institute | Biomanufacturing Education and Training Center (BETC) | $5,149,999 | FY 2010 | Completed |
| NIIMBL | Worcester Polytechnic Institute | SPIDER Project | $139,984 | FY 2018 | Completed |
| NIIMBL | Worcester Polytechnic Institute | Blended Learning Cell Therapy Course | $262,267 | FY 2018 | Completed |
| Workforce Capital | Worcester State University | Collaborative Teaching Methods (CoTEAM) to Enhance Life Sciences Workforce Development | $658,071 | FY 2022 | Ongoing |
| Novel Therapeutics Delivery | Wyss Institute at Harvard | New targets and novel antibody shuttles for brain delivery of therapeutics | $750,000 | FY 2020 | Ongoing |
| | | Total | $571,523,186 | | |